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I have been taking 0.5 mg of avodart twice a day for 4 years. I have noticed no side effects and lab results verify that nearly all testosterone conversion to dihydrotestosterone (DHT) is blocked. Since prostate cancer growth is stimulated by DHT, and not testosterone, my PSA has remained low (below 1)with no tumor regrowth (after radiation therapy).
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The good news is that Phase III trials have already been completed for Benign Prostatic Hyperplasia (BPH, also known as enlarged prostates) and the drug is scheduled to be submitted to the FDA for approval sometime this year and approved and marketed sometime next year.
Growth hormone from human pituitary glands was prescribed until 1985 for children with delayed or impaired growth.
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Dutasteride inhibits the conversion of testosterone to 5α-dihydrotestosterone (DHT).
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Prior to initiating treatment, consider other urological conditions that may cause similar symptoms; BPH and prostate cancer may coexist.
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Prostate cancer cells differ in testosterone accumulation, dihydrotestosterone conversion, and androgen receptor signaling response to steroid 5α-reductase inhibitors.
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