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Hyperlipidaemia and cardiovascular disease.
As shown in Table 4 Incidence of Death from Various Causes and Incidence of Newly Diagnosed Cancers According to Treatment Group.
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Common and uncommon cytochrome P450 reactions related to metabolism and chemical toxicity.
Recommendations for intake of naturally sweetened fruit juice (without added sugar) in infants are a consensus of the Expert Panel (Grade D) and are in agreement with those of the AAP.
Because of this, the FDA then issued letters to other manufacturers of timed-release guaifenesin to stop marketing their unapproved versions, leaving Adams Respiratory Therapeutics in control of the market.
A generic drug is actually its brand-name equivalent, although it doesnt bear the original trademark and looks slightly different.
Fenofibrate therapy was initiated for a 60-year old Hispanic man with stage 4 chronic kidney disease (CKD) for the treatment of hypertriglyceridemia.
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The low numbers needed to treat to prevent major cardiovascular events in our study suggest that gemfibrozil, an inexpensive medication, may prove highly cost effective, if not cost saving, for the treatment of patients with coronary heart disease who have this particular lipid profile.
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Core tip: The objective of this review is to highlight the importance of traditional and non-traditional risk factors for cardiovascular disease in the setting of type 2 diabetes mellitus and discuss their position in the pathogenesis of the excess cardiovascular disease mortality and morbidity in these patients.
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Frequent monitoring may be valuable but has not been shown to be cost effective and is often not performed.
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Trends in Death Rates From Tobacco-related Cardiovascular Diseases in Selected US States Differing in Tobacco-control Efforts.
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Phase I dose escalation pharmacokinetic study in healthy volunteers of resveratrol, a potential cancer chemopreventive agent.
Impact of drug-eluting stents on the comparative effectiveness of coronary artery bypass surgery and percutaneous coronary intervention.
Oral glucose tolerance tests (OGTTs) were performed after 12-h fasts following 4 weeks of treatment.
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In 1999, the American Diabetes Association (ADA) and the American Heart Association (AHA) published a joint statement with the National Heart, Lung, and Blood Institute (NHLBI), the National Institute of Diabetes and Digestive and Kidney Diseases, and the Juvenile Diabetes Foundation International indicating the need for multiorganizational cooperation for prevention of CVD in patients with diabetes ().
The whole manufacturing process is regulated by the US Food and Drug Administration (FDA) and other relevant authorities.
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Angina pectoris, arrhythmia, atrial fibrillation, cardiovascular disorder, coronary artery disorder, electrocardiogram abnormal, extrasystoles, hypertension, hypotension, migraine, myocardial infarct, palpitation, peripheral vascular disorder, phlebitis, tachycardia, varicose vein, vascular disorder, vasodilatation, venous thromboembolic events (deep vein thrombosis, pulmonary embolus) and ventricular extrasystoles.
Each phase of clinical testing before approval includes close monitoring of serum liver-enzyme levels.
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Friedewald WT, Levy RI, Friedrickson D: Estimation of the concentration of Low-density lipoprotein cholesterol in plasma, without use of the preparative ultracentrifuge.
Combination therapy using statins and other lipid-lowering agents may be considered to achieve lipid targets but has not been evaluated in outcome studies for either CVD outcomes or safety (E).
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Impact on Global Health outcomes (AIM-HIGH) trial.
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People who were taking an inhaled steroid may start with two inhalations of the Flovent HFA 110 mcg inhaler.
HDL levels are being tested.
These data suggest that the burden of diabetic eye disease may be even greater in rapidly developing regions.
Clinical target values used to initiate treatment in the general population may be inappropriate in those with SCI because of their unique pathophysiology.
Response endpoints relate to lipid parameters and other variables of interest to cardiovascular endpoints.
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Cardiovascular benefits are obtained if the control of traditional cardiovascular risk factors begins early in subjects with short duration of DM and low cardiovascular risk.
What you need is an advanced lipoprotein panel that actually measures LDL-P and particle count.
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Proteinuria and other markers of chronic kidney disease: a position statement of the National Kidney Foundation (NKF) and the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK).
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Administer orally once daily.
Consistent with the mRNA data, the enzymatic activities for all the tested substrates in the small intestine of colitis mice were dramatically increased ().
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It is neither intended nor implied to be a substitute for professional medical advice.
Ethnicity, race and baseline retinopathy correlates in the Veterans Affairs Diabetes Trial.
Systematic re-evaluation of the diagnosis and treatment of coronary artery disease in hospitalized elderly: Impact on medication underuse.
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One-year consumption of a grape nutraceutical containing resveratrol improves the inflammatory and fibrinolytic status of patients in primary prevention of cardiovascular disease.
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The liver reacts just as if going on a fast, deteriorating essential fatty acids rather than carbohydrates.
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SVS Guideline on the Management of Patients With Extracranial Carotid and Vertebral Artery Disease.
Unneeded medications should be disposed of in special ways to ensure that pets, children, and other people cannot consume them.
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Temporal trends of stress myocardial perfusion imaging: Influence of diabetes, gender and coronary artery disease status.
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Some older individuals developed diabetes years earlier and may have significant complications; others who are newly diagnosed may have had years of undiagnosed diabetes with resultant complications or may have truly recent-onset disease and few or no complications.
Medical Treatment of Peripheral Artery Disease.
Before taking fenofibrate, tell your doctor or pharmacist if you are allergic to it; or to other "fibrates" (such as fenofibric acid); or if you have any other allergies.
Tell your doctor of all nonprescription and prescription medication you may use, especially: "blood thinners" (e.
Detection of cardiovascular autonomic neuropathy using exercise testing in patients with type 2 diabetes mellitus.
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The calorie ranges shown are to accommodate needs of different ages within the group.
In both normotensive and hypertensive individuals, a reduction in sodium intake may lower blood pressure.
Future strategies for preventing and treating coronary heart disease should therefore be comprehensive, maximizing the coverage of effective treatments and actively promoting population-based prevention by reducing risk factors.
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The burden of diabetes-related CVD is likely to continue to expand with the increasing incidence of diabetes in the population.
Meta-analysis of individual patient data in randomised trials of self monitoring of blood glucose in people with non-insulin treated type 2 diabetes.
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Summary of recommendations of the Second Joint Task Force of European and other Societies on Coronary Prevention.
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DPP are cost-effective (), and actual cost data from the DPP and DPPOS confirm that lifestyle interventions are highly cost-effective ().
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With the exception of recommendations related to control of hyperglycemia, the recommendations provided in this document are appropriate for people both with and without diabetes; however, because of their higher risk for CVD, people with diabetes should derive even more benefit from these recommendations.
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The use of imaging for electrophysiological and devices procedures: a report from the first European Heart Rhythm Association Policy Conference, jointly organized with the European Association of Cardiovascular Imaging (EACVI), the Council of Cardiovascular Imaging and the European Society of Cardiac Radiology.
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The Expert Panel believes that these recommendations should be used for management of children and adolescents with diabetes and other predisposing conditions as outlined in the algorithm in Figure 11?
Patients on multiple-dose insulin (MDI) or insulin pump therapy should do SMBG prior to meals and snacks, occasionally postprandially, at bedtime, prior to exercise, when they suspect low blood glucose, after treating low blood glucose until they are normoglycemic, and prior to critical tasks such as driving.
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Review of Time Courses and Predictors of Lipid Changes with Fenofibric Acid-Statin Combination.
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Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.
Pharmacokinetics of resveratrol metabolic profile in healthy humans after moderate consumption of red wine and grape extract tablets.
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Mortality of patients with type 2 diabetes in Taiwan: A 10-year nationwide follow-up study.
However, widespread clinical testing of asymptomatic low-risk individuals cannot currently be recommended, as it would identify very few individuals in the general population who are at risk.
Lofibra (fenofibrate) capsules (micronized) prescribing information.
Fenofibrate is available in multiple generic forms and under the brand names of Antara, Lipofen, Lofibra, TriCor and Triglide as capsules and tablets of multiple concentrations, ranging from 43 to 200 mg each.
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Aspirin for the Primary Prevention of Cardiovascular Disease: In Need of Clarity.
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Crouse, receiving consulting fees from the National Lipid Association, AstraZeneca, Merck, and Merck Schering-Plough and grant support from AstraZeneca; Dr.
Meta-analysis: high-dosage vitamin E supplementation may increase all-cause mortality.
The liver irritation usually is mild and reversible, but it occasionally can be severe enough to require stopping the drug.
Induction of glycolysis-related gene expression was also limited to type-1 predominant soleus muscle in the present study.
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