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Last year I have traveled to Madagascar. It is the biggest island in the Indian Ocean and the biggest island in the whole world. The flora and fauna are astonishing there, as well as the range of different bacteria and infections one can catch there. Before the trip I have taken Quinine to protect me from malaria as it is a very nasty disease to catch. I started on Quinine two days before the departure and continued for several days after I came back. I believe it's due to Quinine that I have not contracted malaria, neither have I had any side effects connected with taking the medication. It is very important that such vital drugs that help prevent life-threatening diseases do not create major difficulties for people who have no other way out but taking them.
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Last year I was going for a month long trip to Thailand. The company I work at was opening a new development department there and I was to provide the support on site. My doctor informed me about the preventive measures I had to take before going to that region in order not to fall ill with malaria. He said Quinine was the best medication from his point of view. As I had no objections I ordered the drug and started taking it. No side effects and no obvious positive effect as well. But then I realized the importance of such medications when I saw people suffering from malaria. The disease is really horrible and I?m grateful to the producers of Quinine as the medication they created protected me from a life-threat. Would recommend it to others!

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Quinine sulfate capsules are a prescription medication used to treat malaria (uncomplicated) caused by the parasite Plasmodium falciparum.

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The antimalarial efficacy of quinine has diminished in some areas, in particular Southeast Asia, suggesting partial resistance that may limit the drug's efficacy against severe malaria.

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Four patients had neurologic sequelae (three in the artemether group and one in the quinine group), and thus there was also no significant difference in the combined number of deaths and cases of neurologic sequelae between the groups.

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Recent improvements in malaria prevention strategies have further enhanced its effectiveness in combating areas highly infected with the malaria parasite.

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In one report, quinine potentiated neuromuscular blockade in a patient who received pancuronium during an operative procedure, and subsequently (3 hours after receiving pancuronium) received quinine 1800 mg daily.

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Carefully weigh benefits and risks if considering concomitant use of quinine and atorvastatin or other HMG-CoA reductase inhibitors that are CYP3A4 substrates (e.

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In developmental and reproductive toxicity studies, central nervous system (CNS) and ear abnormalities and increased fetal deaths occurred in some species when pregnant animals received quinine at doses about 1 to 4 times the human clinical dose.

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One patient given quinine developed severe stridor after administration of ampicillin, and died.

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Extracts from the bark have been used to treat malaria since at least 1632.

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When it came to the life cycle of the plasmodium, the process by which it resisted immune reactions and the effects of quinine, remaining quiescent in the organism until the disease relapsed, was still a mystery.

It was not until 1820 that the active ingredient, quinine, was extracted from the bark, isolated and named by French chemists.

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CDC and other clinicians recommend 650 mg (two 324-mg capsules) every 8 hours for 7 or 3 days as determined by geographic origin of infecting parasite (7 days if malaria acquired in Southeast Asia or 3 days if acquired elsewhere).

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The cure was quinine, an alkaloid made from the bitter red bark of the cinchona tree.

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