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Last year I have traveled to Madagascar. It is the biggest island in the Indian Ocean and the biggest island in the whole world. The flora and fauna are astonishing there, as well as the range of different bacteria and infections one can catch there. Before the trip I have taken Quinine to protect me from malaria as it is a very nasty disease to catch. I started on Quinine two days before the departure and continued for several days after I came back. I believe it's due to Quinine that I have not contracted malaria, neither have I had any side effects connected with taking the medication. It is very important that such vital drugs that help prevent life-threatening diseases do not create major difficulties for people who have no other way out but taking them.
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Last year I was going for a month long trip to Thailand. The company I work at was opening a new development department there and I was to provide the support on site. My doctor informed me about the preventive measures I had to take before going to that region in order not to fall ill with malaria. He said Quinine was the best medication from his point of view. As I had no objections I ordered the drug and started taking it. No side effects and no obvious positive effect as well. But then I realized the importance of such medications when I saw people suffering from malaria. The disease is really horrible and I?m grateful to the producers of Quinine as the medication they created protected me from a life-threat. Would recommend it to others!
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Quinine sulfate capsules are a prescription medication used to treat malaria (uncomplicated) caused by the parasite Plasmodium falciparum.
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The antimalarial efficacy of quinine has diminished in some areas, in particular Southeast Asia, suggesting partial resistance that may limit the drug's efficacy against severe malaria.
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Four patients had neurologic sequelae (three in the artemether group and one in the quinine group), and thus there was also no significant difference in the combined number of deaths and cases of neurologic sequelae between the groups.
All information on this site is provided "as-is" for informational purposes only and is not a substitute for medical advice or treatment.
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Recent improvements in malaria prevention strategies have further enhanced its effectiveness in combating areas highly infected with the malaria parasite.
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In America an overwhelming majority favour the combined system, and it is in America that by far the best results of education are to be seen.
To-date quinine continues to play a significant role in the management of malaria.
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Patients taking medications that are CYP2D6 substrates with quinine sulfate capsules, USP should be monitored closely for adverse reactions associated with these medications.
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In one report, quinine potentiated neuromuscular blockade in a patient who received pancuronium during an operative procedure, and subsequently (3 hours after receiving pancuronium) received quinine 1800 mg daily.
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Carefully weigh benefits and risks if considering concomitant use of quinine and atorvastatin or other HMG-CoA reductase inhibitors that are CYP3A4 substrates (e.
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AUC that was higher by 45% and a mean oral clearance of quinine that was 31% lower than after receiving quinine alone.
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In developmental and reproductive toxicity studies, central nervous system (CNS) and ear abnormalities and increased fetal deaths occurred in some species when pregnant animals received quinine at doses about 1 to 4 times the human clinical dose.
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La quinine a été le premier médicament efficace contre le paludisme.
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One patient given quinine developed severe stridor after administration of ampicillin, and died.
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Extracts from the bark have been used to treat malaria since at least 1632.
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When it came to the life cycle of the plasmodium, the process by which it resisted immune reactions and the effects of quinine, remaining quiescent in the organism until the disease relapsed, was still a mystery.
It was not until 1820 that the active ingredient, quinine, was extracted from the bark, isolated and named by French chemists.
This is accounted for by the possible differences in their inactive ingredients such as color and flavor additives, and by the copyright and trademark regulations that does not allow for exact copies of the existing brand-name products.
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This medication may potentially interact with many other medications, far too many to include in this article.
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The treatment of malaria with quinine marked the first successful use of a in combating an infectious disease.
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CDC and other clinicians recommend 650 mg (two 324-mg capsules) every 8 hours for 7 or 3 days as determined by geographic origin of infecting parasite (7 days if malaria acquired in Southeast Asia or 3 days if acquired elsewhere).
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Specifically, use of over-the-counter medications and prescription medications should be examined because many patients do not consider these agents to be prone to abuse.
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You should not use the information contained here for diagnosing or treating a health problem or disease.
The only brand of pharmaceutical quinine approved for use in the United States is called Qualaquin.
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These 4 cases suggest that belief in the abortifacient efficacy of quinine persists despite questionable evidence.
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These doses are both approximately four times the maximum recommended human daily dose of 2000 mg based on body surface area comparisons.
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Patients should regularly visit their eye doctors and heart doctors (cardiologists) to monitor their conditions.
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The cure was quinine, an alkaloid made from the bitter red bark of the cinchona tree.
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The most serious reactions are rare but can be life threatening.
Weeks, months or even years later, these parasites can become active again and re-invade the blood stream, causing a recurrence of symptoms.
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Quinine may pass into breast milk and could harm a nursing baby.
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If your legislator contact the chairman of the Commttee or the ranking minority member if your member is in the minority, that oversees FDA and THEY contact FDA, it may be taken seriously.
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