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The 2010 metaanalysis examined the efficacy of daily versus thrice-weekly dosing of TB medications and found that, in a pooled analysis, daily dosing during the continuation phase of TB treatment was associated with improved TB outcomes (); studies directly comparing daily with thrice-weekly TB treatment have not been completed but are under way.

Resistance to two first-line drugs like Isoniazid (INH) and Rifampicin is called MDR-TB, and when in addition to these drugs, the disease is also resistant to Fluroinolone and second-line injectable drugs, the disease is called extended drug resistant TB.

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Although Rifampicin has been reported to cross the placental barrier and appear in cord blood, the effect of Rifampicin, alone or in combination with other antituberculosis drugs, on the human foetus is not known.

Journal of Infectious Disease 2012; 205( Suppl 2): S159- 68.

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The US uses abbreviations and names that are not internationally recognised: rifampicin is called rifampin and abbreviated RIF; streptomycin is abbreviated STM.

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